Array ( [PREVIEW_PICTURE] => Array ( [ID] => 71702 [TIMESTAMP_X] => 24.06.2025 16:20:06 [MODULE_ID] => iblock [HEIGHT] => 733 [WIDTH] => 1100 [FILE_SIZE] => 65381 [CONTENT_TYPE] => image/jpeg [SUBDIR] => iblock/73f [FILE_NAME] => 73f345f6272f5f740f106cdb0b66162b.jpg [ORIGINAL_NAME] => breast-cancer.jpg [DESCRIPTION] => [HANDLER_ID] => [EXTERNAL_ID] => 916d4a7de35eea0ddf0111d8058e4d40 [~src] => [SRC] => /upload/iblock/73f/73f345f6272f5f740f106cdb0b66162b.jpg [ALT] => Команда под руководством киприотов добилась прорыва в исследовании рака груди и яичников [TITLE] => Команда под руководством киприотов добилась прорыва в исследовании рака груди и яичников ) [~PREVIEW_PICTURE] => 71702 [ID] => 36383 [~ID] => 36383 [NAME] => Команда под руководством киприотов добилась прорыва в исследовании рака груди и яичников [~NAME] => Команда под руководством киприотов добилась прорыва в исследовании рака груди и яичников [IBLOCK_ID] => 2 [~IBLOCK_ID] => 2 [IBLOCK_SECTION_ID] => 2 [~IBLOCK_SECTION_ID] => 2 [DETAIL_TEXT] => Группа учёных под руководством специалистов с Кипра совершила прорыв в изучении рака груди и яичников благодаря важному исследованию, которое позволяет различать «безобидные» и «опасные» генетические ошибки, объявил Кипрский институт неврологии и генетики (CING) во вторник.

Исследование, опубликованное в журнале Nature Communications, знаменует значительный прогресс в диагностике и оценке опасности рака груди и яичников, позволяя более безопасно интерпретировать мутации в генах BRCA1 и BRCA2.

Международная группа учёных под руководством отдела биостатистики CING проанализировала данные более чем 400 000 женщин со всего мира, чтобы определить, какие генетические мутации в генах BRCA1 и BRCA2 повышают риск развития рака.

Уже много лет известно, что эти два гена играют роль в наследственной предрасположенности к некоторым видам рака.

Однако тысячи мутаций в этих генах остаются «серыми зонами» для врачей и пациентов, поскольку достоверно неизвестно, являются ли они вредными.

Группа под руководством профессора CING Кириаки Михаэлиду и первых авторов Марии Занти и Дениз О'Махони в сотрудничестве с ведущими научными учреждениями со всего мира разработала статистическую модель, которая позволяет сравнивать частоту определённых мутаций у женщин с раком и без него.

Это позволило им определить, какие генетические мутации связаны с повышенным риском.

Михаэлиду сказала, что «результаты исследования не только теоретические, но и могут быть применены в клинической практике».

«Врачи и генетики теперь могут более точно информировать женщин, проходящих генетическое тестирование, о том, несут ли они опасные мутации или нет […] что позволяет женщинам принимать более безопасные решения относительно своего здоровья», — добавила Михаэлиду.

В CING заявили, что исследование проводится в то время, когда генетическое тестирование становится ещё более доступным, что позволяет избежать необоснованной тревоги и не упустить реальные риски.

Генеральный директор института Леонидас Филакту отметил, что «исследование — это ещё один важный шаг на пути к персонализированной медицине».

С исследованием можно ознакомиться [здесь](https://www.nature.com/articles/s41467-025-59979-6). [~DETAIL_TEXT] => Группа учёных под руководством специалистов с Кипра совершила прорыв в изучении рака груди и яичников благодаря важному исследованию, которое позволяет различать «безобидные» и «опасные» генетические ошибки, объявил Кипрский институт неврологии и генетики (CING) во вторник.

Исследование, опубликованное в журнале Nature Communications, знаменует значительный прогресс в диагностике и оценке опасности рака груди и яичников, позволяя более безопасно интерпретировать мутации в генах BRCA1 и BRCA2.

Международная группа учёных под руководством отдела биостатистики CING проанализировала данные более чем 400 000 женщин со всего мира, чтобы определить, какие генетические мутации в генах BRCA1 и BRCA2 повышают риск развития рака.

Уже много лет известно, что эти два гена играют роль в наследственной предрасположенности к некоторым видам рака.

Однако тысячи мутаций в этих генах остаются «серыми зонами» для врачей и пациентов, поскольку достоверно неизвестно, являются ли они вредными.

Группа под руководством профессора CING Кириаки Михаэлиду и первых авторов Марии Занти и Дениз О'Махони в сотрудничестве с ведущими научными учреждениями со всего мира разработала статистическую модель, которая позволяет сравнивать частоту определённых мутаций у женщин с раком и без него.

Это позволило им определить, какие генетические мутации связаны с повышенным риском.

Михаэлиду сказала, что «результаты исследования не только теоретические, но и могут быть применены в клинической практике».

«Врачи и генетики теперь могут более точно информировать женщин, проходящих генетическое тестирование, о том, несут ли они опасные мутации или нет […] что позволяет женщинам принимать более безопасные решения относительно своего здоровья», — добавила Михаэлиду.

В CING заявили, что исследование проводится в то время, когда генетическое тестирование становится ещё более доступным, что позволяет избежать необоснованной тревоги и не упустить реальные риски.

Генеральный директор института Леонидас Филакту отметил, что «исследование — это ещё один важный шаг на пути к персонализированной медицине».

С исследованием можно ознакомиться [здесь](https://www.nature.com/articles/s41467-025-59979-6). [DETAIL_TEXT_TYPE] => html [~DETAIL_TEXT_TYPE] => html [PREVIEW_TEXT] => Группа учёных под руководством специалистов с Кипра совершила прорыв в изучении рака... [~PREVIEW_TEXT] => Группа учёных под руководством специалистов с Кипра совершила прорыв в изучении рака... 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The study, published in Nature Communications, marks significant progress in the diagnosis and assessment of danger regarding breast and ovarian cancer, allowing for the safer interpretation of mutations in the BRCA1 and BRCA2 genes. An international team of scientists, led by the CING biostatistics unit analysed data from over 400,000 women from around the world, to determine which genetic mutations in the BRCA1 and BRCA2 genes increased the risk of cancer. For years now, these two genes have been known for their role in the hereditary predisposition to certain cancers. However, thousands of mutations in these genes remain “grey areas” for doctors and patients, as it is not known with certainty whether they are harmful. The team, led by CING professor Kyriaki Michaelidou and first authors Maria Zanti and Denise O’Mahony, in collaboration with leading scientific institutions from around the world, developed a statistical model that allows for the comparison of the frequency of specific mutations in women with or without cancer. This allowed for them to identify which genetic mutations were associated with increased risk. Michaelidou said “the results of the study are not just theoretical, but can be applied in clinical practice.” “Doctors and geneticists can now inform women undergoing genetic testing more accurately about whether they carry dangerous mutations or no […] which allows women to take safer decisions about their health,” Michaelidou added. CING said the study comes at a time when genetic testing is becoming even more accessible, preventing undue concern and avoiding overlooking real risks. The institute’s CEO Leonidas Phylaktou pointed out that “the study is yet another important step towards personalised medicine”. The study can be found [here](https://www.nature.com/articles/s41467-025-59979-6). [TYPE] => HTML ) [DESCRIPTION] => [VALUE_ENUM] => [VALUE_XML_ID] => [VALUE_SORT] => [~VALUE] => Array ( [TEXT] => A team of Cyprus-led scientists has made a breakthrough in understanding breast and ovarian cancer with a milestone study that distinguishes “innocent” and “dangerous” genetic errors, the Cyprus Institute of Neurology and Genetics (CING) announced on Tuesday. The study, published in Nature Communications, marks significant progress in the diagnosis and assessment of danger regarding breast and ovarian cancer, allowing for the safer interpretation of mutations in the BRCA1 and BRCA2 genes. An international team of scientists, led by the CING biostatistics unit analysed data from over 400,000 women from around the world, to determine which genetic mutations in the BRCA1 and BRCA2 genes increased the risk of cancer. For years now, these two genes have been known for their role in the hereditary predisposition to certain cancers. However, thousands of mutations in these genes remain “grey areas” for doctors and patients, as it is not known with certainty whether they are harmful. The team, led by CING professor Kyriaki Michaelidou and first authors Maria Zanti and Denise O’Mahony, in collaboration with leading scientific institutions from around the world, developed a statistical model that allows for the comparison of the frequency of specific mutations in women with or without cancer. This allowed for them to identify which genetic mutations were associated with increased risk. Michaelidou said “the results of the study are not just theoretical, but can be applied in clinical practice.” “Doctors and geneticists can now inform women undergoing genetic testing more accurately about whether they carry dangerous mutations or no […] which allows women to take safer decisions about their health,” Michaelidou added. CING said the study comes at a time when genetic testing is becoming even more accessible, preventing undue concern and avoiding overlooking real risks. The institute’s CEO Leonidas Phylaktou pointed out that “the study is yet another important step towards personalised medicine”. The study can be found [here](https://www.nature.com/articles/s41467-025-59979-6). 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[SEARCHABLE] => N [FILTRABLE] => N [IS_REQUIRED] => N [VERSION] => 1 [USER_TYPE] => EAutocomplete [USER_TYPE_SETTINGS] => Array ( [VIEW] => A [SHOW_ADD] => Y [MAX_WIDTH] => 250 [MIN_HEIGHT] => 24 [MAX_HEIGHT] => 1000 [BAN_SYM] => ,; [REP_SYM] => [OTHER_REP_SYM] => [IBLOCK_MESS] => Y ) [HINT] => [PROPERTY_VALUE_ID] => [VALUE] => [DESCRIPTION] => [VALUE_ENUM] => [VALUE_XML_ID] => [VALUE_SORT] => [~VALUE] => [~DESCRIPTION] => [~NAME] => Тема [~DEFAULT_VALUE] => ) [LINK_SOURCE] => Array ( [ID] => 8 [TIMESTAMP_X] => 2015-05-25 16:39:08 [IBLOCK_ID] => 2 [NAME] => Источник [ACTIVE] => Y [SORT] => 500 [CODE] => LINK_SOURCE [DEFAULT_VALUE] => russiancyprus [PROPERTY_TYPE] => S [ROW_COUNT] => 1 [COL_COUNT] => 30 [LIST_TYPE] => L [MULTIPLE] => N [XML_ID] => 53 [FILE_TYPE] => [MULTIPLE_CNT] => 5 [TMP_ID] => [LINK_IBLOCK_ID] => 0 [WITH_DESCRIPTION] => N [SEARCHABLE] => N [FILTRABLE] => N [IS_REQUIRED] => N [VERSION] => 1 [USER_TYPE] => [USER_TYPE_SETTINGS] => [HINT] => [PROPERTY_VALUE_ID] => 101485 [VALUE] => cyprus-mail.com [DESCRIPTION] => [VALUE_ENUM] => [VALUE_XML_ID] => [VALUE_SORT] => [~VALUE] => cyprus-mail.com [~DESCRIPTION] => [~NAME] => Источник [~DEFAULT_VALUE] => russiancyprus ) [IS_SENT_TO_CHANEL] => Array ( [ID] => 167 [TIMESTAMP_X] => 2020-06-25 17:42:19 [IBLOCK_ID] => 2 [NAME] => Is sent to telegram [ACTIVE] => Y [SORT] => 500 [CODE] => IS_SENT_TO_CHANEL [DEFAULT_VALUE] => [PROPERTY_TYPE] => N [ROW_COUNT] => 1 [COL_COUNT] => 30 [LIST_TYPE] => L [MULTIPLE] => N [XML_ID] => [FILE_TYPE] => [MULTIPLE_CNT] => 5 [TMP_ID] => [LINK_IBLOCK_ID] => 0 [WITH_DESCRIPTION] => N [SEARCHABLE] => N [FILTRABLE] => N [IS_REQUIRED] => N [VERSION] => 1 [USER_TYPE] => [USER_TYPE_SETTINGS] => [HINT] => [PROPERTY_VALUE_ID] => 101506 [VALUE] => 1 [DESCRIPTION] => [VALUE_ENUM] => [VALUE_XML_ID] => [VALUE_SORT] => [~VALUE] => 1 [~DESCRIPTION] => [~NAME] => Is sent to telegram [~DEFAULT_VALUE] => ) [YANDEX_TASK_ID_THEME] => Array ( [ID] => 285 [TIMESTAMP_X] => 2025-01-20 21:25:08 [IBLOCK_ID] => 2 [NAME] => YANDEX TASK ID FOR THEME [ACTIVE] => Y [SORT] => 900 [CODE] => YANDEX_TASK_ID_THEME [DEFAULT_VALUE] => [PROPERTY_TYPE] => S [ROW_COUNT] => 1 [COL_COUNT] => 30 [LIST_TYPE] => L [MULTIPLE] => N [XML_ID] => [FILE_TYPE] => [MULTIPLE_CNT] => 5 [TMP_ID] => [LINK_IBLOCK_ID] => 0 [WITH_DESCRIPTION] => N [SEARCHABLE] => N [FILTRABLE] => N [IS_REQUIRED] => N [VERSION] => 1 [USER_TYPE] => [USER_TYPE_SETTINGS] => [HINT] => [PROPERTY_VALUE_ID] => 101490 [VALUE] => d7qbqalso4knaqra19to [DESCRIPTION] => [VALUE_ENUM] => [VALUE_XML_ID] => [VALUE_SORT] => [~VALUE] => d7qbqalso4knaqra19to [~DESCRIPTION] => [~NAME] => YANDEX TASK ID FOR THEME [~DEFAULT_VALUE] => ) [YANDEX_TASK_ID] => Array ( [ID] => 284 [TIMESTAMP_X] => 2025-01-20 20:37:32 [IBLOCK_ID] => 2 [NAME] => YANDEX TASK ID [ACTIVE] => Y [SORT] => 1000 [CODE] => YANDEX_TASK_ID [DEFAULT_VALUE] => [PROPERTY_TYPE] => S [ROW_COUNT] => 1 [COL_COUNT] => 30 [LIST_TYPE] => L [MULTIPLE] => N [XML_ID] => [FILE_TYPE] => [MULTIPLE_CNT] => 5 [TMP_ID] => [LINK_IBLOCK_ID] => 0 [WITH_DESCRIPTION] => N [SEARCHABLE] => N [FILTRABLE] => N [IS_REQUIRED] => N [VERSION] => 1 [USER_TYPE] => [USER_TYPE_SETTINGS] => [HINT] => [PROPERTY_VALUE_ID] => 101491 [VALUE] => d7qbre1kqfbrbtpm98d1 [DESCRIPTION] => [VALUE_ENUM] => [VALUE_XML_ID] => [VALUE_SORT] => [~VALUE] => d7qbre1kqfbrbtpm98d1 [~DESCRIPTION] => [~NAME] => YANDEX TASK ID [~DEFAULT_VALUE] => ) ) [DISPLAY_PROPERTIES] => Array ( ) [IBLOCK] => Array ( [ID] => 2 [~ID] => 2 [TIMESTAMP_X] => 20.01.2025 22:57:06 [~TIMESTAMP_X] => 20.01.2025 22:57:06 [IBLOCK_TYPE_ID] => news [~IBLOCK_TYPE_ID] => news [LID] => s1 [~LID] => s1 [CODE] => infoportal_news_s1 [~CODE] => infoportal_news_s1 [NAME] => Новости [~NAME] => Новости [ACTIVE] => Y [~ACTIVE] => Y [SORT] => 500 [~SORT] => 500 [LIST_PAGE_URL] => /news/ [~LIST_PAGE_URL] => /news/ [DETAIL_PAGE_URL] => #SITE_DIR#/news/#SECTION_CODE#/#CODE#/ [~DETAIL_PAGE_URL] => #SITE_DIR#/news/#SECTION_CODE#/#CODE#/ [SECTION_PAGE_URL] => #SITE_DIR#/news/#CODE#/ [~SECTION_PAGE_URL] => #SITE_DIR#/news/#CODE#/ [PICTURE] => [~PICTURE] => [DESCRIPTION] => [~DESCRIPTION] => [DESCRIPTION_TYPE] => text [~DESCRIPTION_TYPE] => text [RSS_TTL] => 24 [~RSS_TTL] => 24 [RSS_ACTIVE] => Y [~RSS_ACTIVE] => Y [RSS_FILE_ACTIVE] => N [~RSS_FILE_ACTIVE] => N [RSS_FILE_LIMIT] => 0 [~RSS_FILE_LIMIT] => 0 [RSS_FILE_DAYS] => 0 [~RSS_FILE_DAYS] => 0 [RSS_YANDEX_ACTIVE] => N [~RSS_YANDEX_ACTIVE] => N [XML_ID] => infoportal_news_s1 [~XML_ID] => infoportal_news_s1 [TMP_ID] => adf9113ce97738184efe133d53e3d656 [~TMP_ID] => adf9113ce97738184efe133d53e3d656 [INDEX_ELEMENT] => Y [~INDEX_ELEMENT] => Y [INDEX_SECTION] => N [~INDEX_SECTION] => N [WORKFLOW] => N [~WORKFLOW] => N [BIZPROC] => N [~BIZPROC] => N [SECTION_CHOOSER] => L [~SECTION_CHOOSER] => L [LIST_MODE] => [~LIST_MODE] => [RIGHTS_MODE] => S [~RIGHTS_MODE] => S [SECTION_PROPERTY] => [~SECTION_PROPERTY] => [PROPERTY_INDEX] => [~PROPERTY_INDEX] => [VERSION] => 1 [~VERSION] => 1 [LAST_CONV_ELEMENT] => 0 [~LAST_CONV_ELEMENT] => 0 [SOCNET_GROUP_ID] => [~SOCNET_GROUP_ID] => [EDIT_FILE_BEFORE] => [~EDIT_FILE_BEFORE] => [EDIT_FILE_AFTER] => [~EDIT_FILE_AFTER] => [SECTIONS_NAME] => Разделы [~SECTIONS_NAME] => Разделы [SECTION_NAME] => Раздел [~SECTION_NAME] => Раздел [ELEMENTS_NAME] => Новости [~ELEMENTS_NAME] => Новости [ELEMENT_NAME] => Новость [~ELEMENT_NAME] => Новость [EXTERNAL_ID] => infoportal_news_s1 [~EXTERNAL_ID] => infoportal_news_s1 [LANG_DIR] => / [~LANG_DIR] => / [SERVER_NAME] => russiancyprus.news [~SERVER_NAME] => russiancyprus.news ) [SECTION] => Array ( [PATH] => Array ( [0] => Array ( [ID] => 2 [~ID] => 2 [TIMESTAMP_X] => 2025-01-20 22:54:27 [~TIMESTAMP_X] => 2025-01-20 22:54:27 [MODIFIED_BY] => 1 [~MODIFIED_BY] => 1 [DATE_CREATE] => 2015-04-24 10:15:32 [~DATE_CREATE] => 2015-04-24 10:15:32 [CREATED_BY] => 1 [~CREATED_BY] => 1 [IBLOCK_ID] => 2 [~IBLOCK_ID] => 2 [IBLOCK_SECTION_ID] => [~IBLOCK_SECTION_ID] => [ACTIVE] => Y [~ACTIVE] => Y [GLOBAL_ACTIVE] => Y [~GLOBAL_ACTIVE] => Y [SORT] => 5 [~SORT] => 5 [NAME] => Общество и политика [~NAME] => Общество и политика [PICTURE] => [~PICTURE] => [LEFT_MARGIN] => 1 [~LEFT_MARGIN] => 1 [RIGHT_MARGIN] => 2 [~RIGHT_MARGIN] => 2 [DEPTH_LEVEL] => 1 [~DEPTH_LEVEL] => 1 [DESCRIPTION] => [~DESCRIPTION] => [DESCRIPTION_TYPE] => text [~DESCRIPTION_TYPE] => text [SEARCHABLE_CONTENT] => Общество и политика [~SEARCHABLE_CONTENT] => Общество и политика [CODE] => society [~CODE] => society [XML_ID] => 111 [~XML_ID] => 111 [TMP_ID] => [~TMP_ID] => [DETAIL_PICTURE] => [~DETAIL_PICTURE] => [SOCNET_GROUP_ID] => [~SOCNET_GROUP_ID] => [LIST_PAGE_URL] => /news/ [~LIST_PAGE_URL] => /news/ [SECTION_PAGE_URL] => /news/society/ [~SECTION_PAGE_URL] => /news/society/ [IBLOCK_TYPE_ID] => news [~IBLOCK_TYPE_ID] => news [IBLOCK_CODE] => infoportal_news_s1 [~IBLOCK_CODE] => infoportal_news_s1 [IBLOCK_EXTERNAL_ID] => infoportal_news_s1 [~IBLOCK_EXTERNAL_ID] => infoportal_news_s1 [EXTERNAL_ID] => 111 [~EXTERNAL_ID] => 111 [IPROPERTY_VALUES] => Array ( ) ) ) ) [SECTION_URL] => /news/society/ [ITEMS_THEME] => Array ( ) )